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Delearth
Delearth
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SARS-CoV-2  Empty SARS-CoV-2

Fri Feb 15, 2019 1:00 am
this is a true story



vidi COVID-19 SARS-CoV-2 preprints from

Epidemics is in general a boring subject ,
worse than climate change & global warming.
Let's hope that in the near future  
a final solution will be found , (available
even for the patients who don't know how 
to get off the beaten track for a while,) 
with some stylish dna modification.
Delearth
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SARS-CoV-2  Empty update 2

Thu Feb 20, 2020 6:00 am
COVID-19 symptoms can range from asymptomatic to severe pneumonia leading to organ failure and death. COVID-19 in most people is mild and resembles the "common cold" . According to the WHO, symptoms include fever (87.9%), dry cough (67.7%), fatigue (38.1%), sputum production (33.4%), shortness of breath (18.6%), sore throat (13.9%), headache (13.6%), muscle or joint aches (14.8%), chills (11.4%), nausea or vomiting (5.0%), nasal congestion (4.8%), diarrhea (3.7%), coughing up blood (0.9%), and conjunctival congestion (0.8%). Symptoms generally occur an average of 5-6 days after infection, but the range is from one to 14 days.

Now here’s the reason the prospect of COVID-19 spreading through the population is so concerning. Quoting the new WHO report:

Most people infected with COVID-19 virus have mild disease and recover. Approximately 80% of laboratory confirmed patients have had mild to moderate disease, which includes non-pneumonia and pneumonia cases, 13.8% have severe disease (dyspnea, respiratory frequency ≥30/minute, blood oxygen saturation ≤93%, PaO2/FiO2 ratio <300, and/or lung infiltrates >50% of the lung field within 24-48 hours) and 6.1% are critical (respiratory failure, septic shock, and/or multiple organ dysfunction/failure). Asymptomatic infection has been reported, but the majority of the relatively rare cases who are asymptomatic on the date of identification/report went on to develop disease. The proportion of truly asymptomatic infections is unclear but appears to be relatively rare and does not appear to be a major driver of transmission.

Sch :  a respiratory frequency of greater than 30 breaths/minute is very alarming (a normal respiratory rate is between 12-20 breaths/minute), and an O2 saturation of <93% on room air in someone who was previously healthy is not good. As for lung infiltrates on chest X-ray, when disease is severe, SARS-CoV-2 causes bilateral diffuse lung infiltrates. An infiltrate is nothing more than a substance denser than air that shows up as white blotches on chest X-ray. In the lungs, such infiltrates usually mean fluid or inflammation.

* fatality rates : 

the lowest estimates (around 0.7%) are at least five to seven times higher than the case fatality rates for seasonal influenza (0.1%), and the highest CDC-estimated rate is around 30 times more deadly than the flu.

Suffice to say that, right now, estimates for case fatality rates are all over the map between around 0.5% and 6.0%. Over time, estimates will likely converge on a more reliable rate. There’s a caveat, though. It’s important to remember that case fatality rates are context-specific, changing with time and location. There is no single case fatality rate for a disease. We also need to be very careful interpreting case fatality rate estimates during the middle of an outbreak or pandemic. Many are currently infected, and we don’t yet know which ones will recover or die—or even accurately which ones are infected.

No matter what the “true” case fatality rates turn out to be, there is no denying that COVID-19 is much deadlier if you’re over 60 and alarmingly deadly for those over 80.
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SARS-CoV-2  Empty updt 4

Thu Mar 19, 2020 6:00 am
SARS-CoV-2  C19-110

some new data from italy.


SARS-CoV-2  C19-510
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SARS-CoV-2  Empty Re: SARS-CoV-2

Thu Mar 19, 2020 6:00 am
Avoiding Contact.
SARS-CoV-2  Flatte10
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SARS-CoV-2  Empty Re: SARS-CoV-2

Thu Mar 19, 2020 6:00 am
Let's take a break from Cov-2
(and each other)
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SARS-CoV-2  Empty Re: SARS-CoV-2

Thu Mar 19, 2020 6:00 am
okay , here we go :

https://www.nih.gov/news-events/news-releases/new-coronavirus-stable-hours-surfaces

"acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was detectable in aerosols for up to three hours, up to four hours on copper, up to 24 hours on cardboard and up to two to three days on plastic and stainless steel."

This is wonderful information, it means you have to consider all public surfaces as contaminated. You do not need direct contact with someone who is sick to get CoV-2, you just have to touch a doorknob that someone touched the day before. Again, this is why isolation is very important. And for a millionth time – wash your hands in soap and water, old school - scrubbing them for 42 seconds, and rinse in running water.  Hand sanitizer with at least 60% alcohol will do as well, but you need to use a large amount and scrub thoroughly.

And also Use Lysol (dettol)  or an alcohol-based cleaner, and keep any surface people touch clean.  This is very important in public places.
the virus survives for hours in aerosols, so keep your distance from people, (2m is not far enough) don’t go out, and if you think you "have to", the masks may help a little but don’t get a false sense of security from them. ( f.i. οι σερβιέτες δεν βοηθάνε , η μάσκα του Ζορρό το ιδιο , οι χειρουργικές δεν εχουν φτιαχτεί για να προστατεύουν τον χειρουργό , οι n95 με σωστή τοποθέτηση- έχουν αποδειχτεί αποτελεσματικές , ενώ η αποκριάτικη μάσκα Άδωνις Γεωργιάδης απτα τζάμπο μπορει να βοηθήσει μονο - στο να απομακρύνονται οι αλλοι απο εσάς πιο γρήγορα) .
In any case  You just have to consider all people as  zombies  (even if they haven't got the new virus yet).
it's more fun this way.  (α ν ε ξ ά ρ τ η τ α)
------------------------------------------------------------------
[*]
about the COVID-19 cases in Germany  :
"we were simply at the forefront in terms of diagnostics,” (said Christian Drosten),
a big number of independent labs received both the technical information needed to conduct tests and the approval to bill for them in January, when cases in Germany were still in the single digits. I'm very certain of this gave an extreme advantage in recognizing the epidemic in Germany,"
"The low number of complications relative to the number of cases reported so far was partly due to the types of people being diagnosed
It's a fact that the age structure of those who have died in Italy is around 80,” (said Lothar Wieler). “Many of the young people who are also infected (but not seriously ill) simply haven't been recognized". . In Germany, the median age of those diagnosed with COVID-19, the disease the virus causes, is about 40, he said.

---------------------------------------------------------------


some Good news from the vaccine development research .

the scientific study of CoV-2 has been incredibly fast, almost unprecedented. The fellow Researchers  are  essentially “scienceing the shit” out of this pandemic. There are human trials of a potential vaccine starting Already! "This is just preliminary testing, mostly for safety but also to look at biological markers to see if the vaccine is doing what it is supposed to do. This is not a live-virus vaccine, so cannot cause disease, but rather contains a DNA fragment from the virus."

It is hard to predict exactly how long it will take to fully develop and deploy a vaccine. Estimates are from 12-18 months, hopefully at the sooner end of the spectrum. how protective it will be - is also unknown . But anything will help, it will reduce the number of receptive hosts, and make it more difficult for the virus to spread . (this is what some people call "herd immunity" )
The finest choice now - as always - is to Not be part of the "herd" - to not get infected.  
As you can see in the published epidemiological reports No one has immunity. it has to be even easier for younger individuals to avoid human contact and to not be part of the spread. Nearly everyone has a computer and everything (along with games pornographic movies etc)and hopefully many have the intelligence to get that "socializing" is highly overrated.

a final note from the post of Steven Novella (A clinical neurologist at the Yale University)
This is, perhaps, one good thing that will come out of this pandemic. Perhaps the world will take note – when it really matters, we need Science. Reality doesn’t care what we believe. It does not alter itself to conform to our delusions and desires.
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SARS-CoV-2  Empty Re: SARS-CoV-2

Thu Mar 19, 2020 6:00 am
Delearth
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SARS-CoV-2  Empty Re: SARS-CoV-2

Fri Mar 20, 2020 2:20 pm
ΑCTIVE CASES
SARS-CoV-2  4107966755 22/3 : 198.780 (95% mild)
SARS-CoV-2  4107966755 23/3 : 215.753 (95% )
SARS-CoV-2  4107966755 26/3 : 321.900 (96% )
10/4 1,098,411 (96%)
16/4 1,387,117 (96%)
23/4 1,674,061 (97%)
5/5  2,148,415 (98%)
23/5 2,774,944 (98%)
10/6 3,251,462 (98%)
01/7 4,259,938 (99%)
31/10 11,400,809 (99%)

15 / 4
https://www.dailyprincetonian.com/article/2020/04/john-conway-dead-covid-19


Last edited by Delearth on Sat Oct 31, 2020 10:17 am; edited 3 times in total
Delearth
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SARS-CoV-2  Empty Re: SARS-CoV-2

Wed Jun 03, 2020 10:30 pm
SARS-CoV-2  SarsCov2_Niaid_960


Novel Coronavirus Attacks a Cell : https://apod.nasa.gov/apod/image/2006/SarsCov2_Niaid_4096.jpg  

All over the planet  , DNA-based organisms are under attack.  The attack is not from large tentacle-flailing aliens, but  from

strange microscopic invaders who aren't  even alive .  The RNA-based virus, which creates a disease known as COVID-19 ,

specializes  in reprogramming cells into zombies that manufacture and release copies of  ITself.

Pictured here  is a high magnification image of a heavily infected cell with invading SARS-CoV2 virus particles (orange).

it's Nothing personal. It's Strictly Business .
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SARS-CoV-2  Empty Re: SARS-CoV-2

Mon Dec 21, 2020 11:30 pm
SARS-CoV-2  3833324623
Delearth
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SARS-CoV-2  Empty Re: SARS-CoV-2

Mon May 03, 2021 9:30 pm
SARS-CoV-2  Joxv10

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SARS-CoV-2  Empty Re: SARS-CoV-2

Mon May 03, 2021 9:30 pm
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SARS-CoV-2  Empty Re: SARS-CoV-2

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